Recent studies on the antioxidant and immunoactive properties of Desmodium adscendens:
Chemical Composition and Cellular Evaluation of the Antioxidant Activity of Desmodium adscendens Leaves. 2011. Muanda, FN, Bouayed A, Djilani A, Yao C, Soulimani R, Dicko A, Evidence-Based Complementary and Alternative Medicine, Volume 2011, Article ID 620862, 9 p - LINK
Study on Biological Activities and Chemical Composition of Extracts from Desmodium adscendens Leaves. 2011. Muanda FN, Soulimani R, Dicko A, Journal of Natural Products, 4:100-107. (2011) - LINK
Immunoactive Profile of Desmodium adscendens L. Aqueous Extract in Mice. 2011. Rammal H, Soulimani R, Advances In Bioresearch, Vol. 2 [1] June: 84-91 (2011) - LINK
Quantification of Total Phenols and Flavonoids of Desmodium adscendens (Sw.) DC. (Papillionaceae) and Projection of their Antioxidant Capacity. 2012. Konan KM, Mamyrbékova-Békro JA, Békro YA, Journal of Applied Biosciences 49: 3355– 3362 (2012) - LINK
Study on Biological Activities and Chemical Composition of Extracts from Desmodium adscendens Leaves. 2011. Muanda FN, Soulimani R, Dicko A, Journal of Natural Products, 4:100-107. (2011) - LINK
Immunoactive Profile of Desmodium adscendens L. Aqueous Extract in Mice. 2011. Rammal H, Soulimani R, Advances In Bioresearch, Vol. 2 [1] June: 84-91 (2011) - LINK
Quantification of Total Phenols and Flavonoids of Desmodium adscendens (Sw.) DC. (Papillionaceae) and Projection of their Antioxidant Capacity. 2012. Konan KM, Mamyrbékova-Békro JA, Békro YA, Journal of Applied Biosciences 49: 3355– 3362 (2012) - LINK
THIRD PARTY RESEARCH: SELECTED BIBLIOGRAPHY
Addy, M.E., Awumney E.M., 1984. Effects of the extract of Desmodium adscendens on anaphylaxis. Journal of Ethnopharmacology 11 (3): 282-292 (1984)
Addy, M.E., Dzandu W.K., 1986. Dose-response Effects of Desmodium adscendens aqueous extract on histamine response, content and anaphylactic reactions in the guinea pig. J Ethnopharmacol 18 (1): 13-20 (1986)
Addy, M.E., Burka, J.F., 1987. Dose-response effects of Desmodium adscendens aqueous extract on antigen- and arachidonic acid- induced contractions of guinea- pig airways. Phytother Res 1 (4): 180-186 (1987)
Addy, M.E., Burka, J.F., 1988. Effect of Desmodium adscendens fractions on antigen- and arachidonic acid-induced contractions of guinea pig airways.
Can-J-Physiol-Pharmacol 66 (6): 820-5 (1988)
Addy, M.E., Burka J.F., 1989. Effect of Desmodium adscendens fraction F1 (DAFL) on tone and agonist-induced contractions of guinea pig airway smooth muscle. Phytother Res 3 (3): 85-90 (1989)
Addy, M.E., 1989. Several chromatography distinct fractions of Desmodium adscendens inhibit smooth muscle contractions. Int J Crude Res 27 (2): 81-91 (1989)
Addy, M.E., Burka, J.F., 1990. Effect of Desmodium adscendens fraction 3 on contractions of respiratory smooth muscle. J Ethnopharmacol 29 (3): 325–35 (1990)
Addy, M.E., 1992. Some secondary plant metabolites in Desmodioum adscendens and their effects on arachidonic acid metabolism. Prostaglandins Leukotrienes Essential Fatty Acids 47 (1): 85-91 (1992)
Addy, M.E., Schwartzman, M.L., 1992. An extract of Desmodium adscendens inhibits NADPH-dependent oxygenation of arachidonic acid Kidney cortical microsomes. Phytother Res 6: 245-250 (1992)
Addy M.E., 1993. Pharmacological actions of Desmodium adscendens, a Ghanaian medicinal plant. Discovery and Innovation 5: 205-10 (1993)
Addy, M.E., Schwartzman, M.L., 1995. An extract of Desmodium adscendens activates cyclooxygenase and increases prostaglandin synthesis by ram seminal vesicle microsomes. Phytother Res 9 (4): 287-293 (1995)
Ampofo, O., 1977. Plants that heal. World Health 26–30 (1977)
Asante-Poku, S., Sasakibara, J., Addy, M.E., 1988. Alkaloids of Desmodium adscendens. Ghana Med J 22: 111-115 (1988)
Barreto, G. S., 2002. Effect of butanolic fraction of Desmodium adscendens on the anococcygeus of the rat. Braz J Biol 62 (2): 223–30 (2002)
Boye, G., Ampopo, O., 1990. Plants and traditional medicine in Ghana, Economic and Medicinal Plant Research 4: 33-34 (1990).
Giangiacomo KM, Kamassah A, Harris G, McManus OB, Mechanism of maxi-K channel activation by Dehydrosoyasaponin-I. J Gen Physiol 112 (4): 485–501 (1998)
Heard O, 1994. Contribution à l’étude du Desmodium adscendens aqueous extract : chimie et pharmacologie. Thèse de pharmacie, Université de Tours (1994)
Humphries JM, Hughes SJ, 2006. Pharmaceutical, nutraceutical and industrial potential of temperate legumes. CRC Salinity Bulletin 2 (2006)
Konan KM, Mamyrbékova-Békro JA, Békro YA, 2012. Quantification of total phenols and flavonoids of
Desmodium adscendens (Sw.) DC. (Papillionaceae) and projection of their antioxidant capacity. Journal of Applied Biosciences 49: 3355– 3362 (2012)
Kusano, S., Otani, A., 2005. Carbohydrate absorption inhibitor and hyperglycemia-preventing food. Japanese Patent- JP2005035954 (2005)
Lo Roscio, E., 2002. Desmodium adscendens (Sw.) D.C.: botanique, chimie et intérêts thérapeutiques. Thèse de doctorat en pharmacie, Lyon (2002)
Mamyrbékova-Békro, J.A., 2008. Phytocompounds of the Extracts of Four Medicinal Plants of Côte D'Ivoire and Assessment of their Potential Antioxidant by Thin Layer Chromatography. Scientific Research 24 (2): 219-22 (2008)
Mao, S.-c., LI, Z.-y, Li, C., 2007. Studies on antioxidation activity of three plants of Desmodium. Journal -Yunnan University (Natural Science Edition) 29 (4): 393-397 (2007)
McManus, O. B., Harris, G. H., Giangiacomo, K. M., Feigenbaum, P., Reuben, J. P., Addy, M. E., Burka, J. F., Kaczorowski, G. J., Garcia, M. L., 1993. An activator of calcium-dependent potassium channels
isolated from a medicinal herb. Biochemistry 32 (24): 6128-33 (1993)
McManus ,O.B., Giangiacomo K.L., Harris G.H., Addy M.E., Reuben J.P., Kaczorowski G.J., Garcia M.L.,1993. A maxi-potassium channel agonist isolated from a medicinal herb. Biophysical Journal 64 (1993)
Morris, J.B., Wang, M.L., 2007. Anthocyanin and potential therapeutic traits in Clitoria, Desmodium, Corchorus, Catharanthus, and Hibiscus species. Acta Hort (ISHS) 756: 381-388, International Symposium on Medicinal and Nutraceutical Plants (2007) Available: http://www.ishs.org
Muanda FN, Bouayed A, Djilani A, Yao C, Soulimani R, Dicko A, 2011. Chemical composition and, cellular evaluation of the antioxidant activity of Desmodium adscendens leaves. Evidence-Based Complementary and Alternative Medicine, Volume 2011, Article ID 620862, 9
Muanda FN, Soulimani R, Dicko A, 2011. Study on biological activities and chemical composition of extracts from Desmodium adscendens leaves. Journal of Natural Products, 4:100-107. (2011)
N'gouemo P, Baldy-Moulinier M, Nguemby-Bina C, 1996. Effects of an ethanolic extract of Desmodium adscendens on central nervous system in rodents. J Ethnopharmacol 52 (2): 77-83 (1996)
Pieme CA, 2004. Ten Plants from Cameroon screened for potential antimicrobial and antitumor activity. Western Africa network of natural products research scientists meeting, (August 2004)
Pieters L, Chemical and pharmacological investigation of the medicinal plant Desmodium adscendens, Laboratory of Pharmacognosy and Pharmaceutical Analysis, University of Antwerp, Duration:01/01/2008 - 31/12/2009 (publication pending)
Pothier, J.; Ragot, J.; Galand, N., 2006. Planar chromatographic study of
flavonoids and soyasaponins for validation of fingerprints of Desmodium
adscendens of different origins. J Planar Chromatogr 19: 191-194 (2006)
Rastogi S, Pandey MM, Rawat AK. 2011. An ethnomedicinal, phytochemical and pharmacological profile of Desmodium gangeticum (L.) DC. and Desmodium adscendens (Sw.) DC., J Ethnopharmacol. Jun 22;136(2):283-96. (2011)
Rigby, A.F., 2003. Herbal tonic composition that improves respiration, aids in the elimination of toxins and improves overall vitality, U.S. Patent #6582702 (2003)
Sabiiti, E.N., Henderlong, P.R. and Mugerwa, J.S., 1989. Evaluation of Desmodium adscendens through vegetative propagation in planted and natural pastures. In: Dzowela B.H.(ed.), Proceedings of the third PANESA workshop, Arusha, Tanzania, 27-30 April, 1987. ILCA, Addis Ababa, Ethiopia. pp 110-117
Addy, M.E., Awumney E.M., 1984. Effects of the extract of Desmodium adscendens on anaphylaxis. Journal of Ethnopharmacology 11 (3): 282-292 (1984)
Addy, M.E., Dzandu W.K., 1986. Dose-response Effects of Desmodium adscendens aqueous extract on histamine response, content and anaphylactic reactions in the guinea pig. J Ethnopharmacol 18 (1): 13-20 (1986)
Addy, M.E., Burka, J.F., 1987. Dose-response effects of Desmodium adscendens aqueous extract on antigen- and arachidonic acid- induced contractions of guinea- pig airways. Phytother Res 1 (4): 180-186 (1987)
Addy, M.E., Burka, J.F., 1988. Effect of Desmodium adscendens fractions on antigen- and arachidonic acid-induced contractions of guinea pig airways.
Can-J-Physiol-Pharmacol 66 (6): 820-5 (1988)
Addy, M.E., Burka J.F., 1989. Effect of Desmodium adscendens fraction F1 (DAFL) on tone and agonist-induced contractions of guinea pig airway smooth muscle. Phytother Res 3 (3): 85-90 (1989)
Addy, M.E., 1989. Several chromatography distinct fractions of Desmodium adscendens inhibit smooth muscle contractions. Int J Crude Res 27 (2): 81-91 (1989)
Addy, M.E., Burka, J.F., 1990. Effect of Desmodium adscendens fraction 3 on contractions of respiratory smooth muscle. J Ethnopharmacol 29 (3): 325–35 (1990)
Addy, M.E., 1992. Some secondary plant metabolites in Desmodioum adscendens and their effects on arachidonic acid metabolism. Prostaglandins Leukotrienes Essential Fatty Acids 47 (1): 85-91 (1992)
Addy, M.E., Schwartzman, M.L., 1992. An extract of Desmodium adscendens inhibits NADPH-dependent oxygenation of arachidonic acid Kidney cortical microsomes. Phytother Res 6: 245-250 (1992)
Addy M.E., 1993. Pharmacological actions of Desmodium adscendens, a Ghanaian medicinal plant. Discovery and Innovation 5: 205-10 (1993)
Addy, M.E., Schwartzman, M.L., 1995. An extract of Desmodium adscendens activates cyclooxygenase and increases prostaglandin synthesis by ram seminal vesicle microsomes. Phytother Res 9 (4): 287-293 (1995)
Ampofo, O., 1977. Plants that heal. World Health 26–30 (1977)
Asante-Poku, S., Sasakibara, J., Addy, M.E., 1988. Alkaloids of Desmodium adscendens. Ghana Med J 22: 111-115 (1988)
Barreto, G. S., 2002. Effect of butanolic fraction of Desmodium adscendens on the anococcygeus of the rat. Braz J Biol 62 (2): 223–30 (2002)
Boye, G., Ampopo, O., 1990. Plants and traditional medicine in Ghana, Economic and Medicinal Plant Research 4: 33-34 (1990).
Giangiacomo KM, Kamassah A, Harris G, McManus OB, Mechanism of maxi-K channel activation by Dehydrosoyasaponin-I. J Gen Physiol 112 (4): 485–501 (1998)
Heard O, 1994. Contribution à l’étude du Desmodium adscendens aqueous extract : chimie et pharmacologie. Thèse de pharmacie, Université de Tours (1994)
Humphries JM, Hughes SJ, 2006. Pharmaceutical, nutraceutical and industrial potential of temperate legumes. CRC Salinity Bulletin 2 (2006)
Konan KM, Mamyrbékova-Békro JA, Békro YA, 2012. Quantification of total phenols and flavonoids of
Desmodium adscendens (Sw.) DC. (Papillionaceae) and projection of their antioxidant capacity. Journal of Applied Biosciences 49: 3355– 3362 (2012)
Kusano, S., Otani, A., 2005. Carbohydrate absorption inhibitor and hyperglycemia-preventing food. Japanese Patent- JP2005035954 (2005)
Lo Roscio, E., 2002. Desmodium adscendens (Sw.) D.C.: botanique, chimie et intérêts thérapeutiques. Thèse de doctorat en pharmacie, Lyon (2002)
Mamyrbékova-Békro, J.A., 2008. Phytocompounds of the Extracts of Four Medicinal Plants of Côte D'Ivoire and Assessment of their Potential Antioxidant by Thin Layer Chromatography. Scientific Research 24 (2): 219-22 (2008)
Mao, S.-c., LI, Z.-y, Li, C., 2007. Studies on antioxidation activity of three plants of Desmodium. Journal -Yunnan University (Natural Science Edition) 29 (4): 393-397 (2007)
McManus, O. B., Harris, G. H., Giangiacomo, K. M., Feigenbaum, P., Reuben, J. P., Addy, M. E., Burka, J. F., Kaczorowski, G. J., Garcia, M. L., 1993. An activator of calcium-dependent potassium channels
isolated from a medicinal herb. Biochemistry 32 (24): 6128-33 (1993)
McManus ,O.B., Giangiacomo K.L., Harris G.H., Addy M.E., Reuben J.P., Kaczorowski G.J., Garcia M.L.,1993. A maxi-potassium channel agonist isolated from a medicinal herb. Biophysical Journal 64 (1993)
Morris, J.B., Wang, M.L., 2007. Anthocyanin and potential therapeutic traits in Clitoria, Desmodium, Corchorus, Catharanthus, and Hibiscus species. Acta Hort (ISHS) 756: 381-388, International Symposium on Medicinal and Nutraceutical Plants (2007) Available: http://www.ishs.org
Muanda FN, Bouayed A, Djilani A, Yao C, Soulimani R, Dicko A, 2011. Chemical composition and, cellular evaluation of the antioxidant activity of Desmodium adscendens leaves. Evidence-Based Complementary and Alternative Medicine, Volume 2011, Article ID 620862, 9
Muanda FN, Soulimani R, Dicko A, 2011. Study on biological activities and chemical composition of extracts from Desmodium adscendens leaves. Journal of Natural Products, 4:100-107. (2011)
N'gouemo P, Baldy-Moulinier M, Nguemby-Bina C, 1996. Effects of an ethanolic extract of Desmodium adscendens on central nervous system in rodents. J Ethnopharmacol 52 (2): 77-83 (1996)
Pieme CA, 2004. Ten Plants from Cameroon screened for potential antimicrobial and antitumor activity. Western Africa network of natural products research scientists meeting, (August 2004)
Pieters L, Chemical and pharmacological investigation of the medicinal plant Desmodium adscendens, Laboratory of Pharmacognosy and Pharmaceutical Analysis, University of Antwerp, Duration:01/01/2008 - 31/12/2009 (publication pending)
Pothier, J.; Ragot, J.; Galand, N., 2006. Planar chromatographic study of
flavonoids and soyasaponins for validation of fingerprints of Desmodium
adscendens of different origins. J Planar Chromatogr 19: 191-194 (2006)
Rastogi S, Pandey MM, Rawat AK. 2011. An ethnomedicinal, phytochemical and pharmacological profile of Desmodium gangeticum (L.) DC. and Desmodium adscendens (Sw.) DC., J Ethnopharmacol. Jun 22;136(2):283-96. (2011)
Rigby, A.F., 2003. Herbal tonic composition that improves respiration, aids in the elimination of toxins and improves overall vitality, U.S. Patent #6582702 (2003)
Sabiiti, E.N., Henderlong, P.R. and Mugerwa, J.S., 1989. Evaluation of Desmodium adscendens through vegetative propagation in planted and natural pastures. In: Dzowela B.H.(ed.), Proceedings of the third PANESA workshop, Arusha, Tanzania, 27-30 April, 1987. ILCA, Addis Ababa, Ethiopia. pp 110-117